PhytophthoraV1, Main, Exploration, bibRecord, 000D27

A Phytophthora sojae effector PsCRN63 forms homo-/hetero-dimers to suppress plant immunity via an inverted association manner.

Identifieur interne : 000D27 ( Main/Exploration ); précédent : 000D26; suivant : 000D28

A Phytophthora sojae effector PsCRN63 forms homo-/hetero-dimers to suppress plant immunity via an inverted association manner.

Auteurs : Qi Li [République populaire de Chine] ; Meixiang Zhang [République populaire de Chine] ; Danyu Shen [République populaire de Chine] ; Tingli Liu [République populaire de Chine] ; Yanyu Chen [République populaire de Chine] ; Jian-Min Zhou [République populaire de Chine] ; Daolong Dou [République populaire de Chine]

Source :

Scientific reports [ 2045-2322 ] ; 2016.

RBID : pubmed:27243217

Descripteurs français

English descriptors

KwdEn :
- Apoptosis Regulatory Proteins (chemistry), Apoptosis Regulatory Proteins (genetics), Apoptosis Regulatory Proteins (metabolism), Arabidopsis (genetics), Arabidopsis (immunology), Arabidopsis (microbiology), Arabidopsis Proteins (genetics), Arabidopsis Proteins (immunology), Cell Death (MeSH), Gene Expression Regulation (MeSH), Host-Pathogen Interactions (MeSH), Phosphorylation (MeSH), Phytophthora (genetics), Phytophthora (growth & development), Phytophthora (metabolism), Plant Cells (immunology), Plant Cells (microbiology), Plant Diseases (genetics), Plant Diseases (immunology), Plant Diseases (microbiology), Plant Immunity (genetics), Plant Leaves (genetics), Plant Leaves (immunology), Plant Leaves (microbiology), Plants, Genetically Modified (MeSH), Protein Kinases (genetics), Protein Kinases (immunology), Protein Multimerization (MeSH), Protein-Serine-Threonine Kinases (genetics), Protein-Serine-Threonine Kinases (immunology), Protoplasts (immunology), Protoplasts (microbiology), Pseudomonas syringae (genetics), Pseudomonas syringae (metabolism), Signal Transduction (MeSH).
MESH :
- chemical , chemistry : Apoptosis Regulatory Proteins.
- chemical , genetics : Apoptosis Regulatory Proteins, Arabidopsis Proteins, Protein Kinases, Protein-Serine-Threonine Kinases.
- chemical , immunology : Arabidopsis Proteins, Protein Kinases, Protein-Serine-Threonine Kinases.
- chemical , metabolism : Apoptosis Regulatory Proteins.
- genetics : Arabidopsis, Phytophthora, Plant Diseases, Plant Immunity, Plant Leaves, Pseudomonas syringae.
- growth & development : Phytophthora.
- immunology : Arabidopsis, Plant Cells, Plant Diseases, Plant Leaves, Protoplasts.
- metabolism : Phytophthora, Pseudomonas syringae.
- microbiology : Arabidopsis, Plant Cells, Plant Diseases, Plant Leaves, Protoplasts.
- Cell Death, Gene Expression Regulation, Host-Pathogen Interactions, Phosphorylation, Plants, Genetically Modified, Protein Multimerization, Signal Transduction.

Abstract

Oomycete pathogens produce a large number of effectors to promote infection. Their mode of action are largely unknown. Here we show that a Phytophthora sojae effector, PsCRN63, suppresses flg22-induced expression of FRK1 gene, a molecular marker in pathogen-associated molecular patterns (PAMP)-triggered immunity (PTI). However, PsCRN63 does not suppress upstream signaling events including flg22-induced MAPK activation and BIK1 phosphorylation, indicating that it acts downstream of MAPK cascades. The PsCRN63-transgenic Arabidopsis plants showed increased susceptibility to bacterial pathogen Pseudomonas syringae pathovar tomato (Pst) DC3000 and oomycete pathogen Phytophthora capsici. The callose deposition were suppressed in PsCRN63-transgenic plants compared with the wild-type control plants. Genes involved in PTI were also down-regulated in PsCRN63-transgenic plants. Interestingly, we found that PsCRN63 forms an dimer that is mediated by inter-molecular interactions between N-terminal and C-terminal domains in an inverted association manner. Furthermore, the N-terminal and C-terminal domains required for the dimerization are widely conserved among CRN effectors, suggesting that homo-/hetero-dimerization of Phytophthora CRN effectors is required to exert biological functions. Indeed, the dimerization was required for PTI suppression and cell death-induction activities of PsCRN63.

DOI: 10.1038/srep26951
PubMed: 27243217
PubMed Central: PMC4886637

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000B92
to stream Main, to step Curation: 000B92

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A Phytophthora sojae effector PsCRN63 forms homo-/hetero-dimers to suppress plant immunity via an inverted association manner.</title>
<author><name sortKey="Li, Qi" sort="Li, Qi" uniqKey="Li Q" first="Qi" last="Li">Qi Li</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea>
<wicri:noRegion>Nanjing 210095</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Center for Genome Biology and State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Center for Genome Biology and State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zhang, Meixiang" sort="Zhang, Meixiang" uniqKey="Zhang M" first="Meixiang" last="Zhang">Meixiang Zhang</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea>
<wicri:noRegion>Nanjing 210095</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shen, Danyu" sort="Shen, Danyu" uniqKey="Shen D" first="Danyu" last="Shen">Danyu Shen</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea>
<wicri:noRegion>Nanjing 210095</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Liu, Tingli" sort="Liu, Tingli" uniqKey="Liu T" first="Tingli" last="Liu">Tingli Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea>
<wicri:noRegion>Nanjing 210095</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chen, Yanyu" sort="Chen, Yanyu" uniqKey="Chen Y" first="Yanyu" last="Chen">Yanyu Chen</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea>
<wicri:noRegion>Nanjing 210095</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhou, Jian Min" sort="Zhou, Jian Min" uniqKey="Zhou J" first="Jian-Min" last="Zhou">Jian-Min Zhou</name>
<affiliation wicri:level="1"><nlm:affiliation>Center for Genome Biology and State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Center for Genome Biology and State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dou, Daolong" sort="Dou, Daolong" uniqKey="Dou D" first="Daolong" last="Dou">Daolong Dou</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea>
<wicri:noRegion>Nanjing 210095</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2016">2016</date>
<idno type="RBID">pubmed:27243217</idno>
<idno type="pmid">27243217</idno>
<idno type="doi">10.1038/srep26951</idno>
<idno type="pmc">PMC4886637</idno>
<idno type="wicri:Area/Main/Corpus">000B92</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000B92</idno>
<idno type="wicri:Area/Main/Curation">000B92</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000B92</idno>
<idno type="wicri:Area/Main/Exploration">000B92</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">A Phytophthora sojae effector PsCRN63 forms homo-/hetero-dimers to suppress plant immunity via an inverted association manner.</title>
<author><name sortKey="Li, Qi" sort="Li, Qi" uniqKey="Li Q" first="Qi" last="Li">Qi Li</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea>
<wicri:noRegion>Nanjing 210095</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:affiliation>Center for Genome Biology and State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Center for Genome Biology and State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Zhang, Meixiang" sort="Zhang, Meixiang" uniqKey="Zhang M" first="Meixiang" last="Zhang">Meixiang Zhang</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea>
<wicri:noRegion>Nanjing 210095</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shen, Danyu" sort="Shen, Danyu" uniqKey="Shen D" first="Danyu" last="Shen">Danyu Shen</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea>
<wicri:noRegion>Nanjing 210095</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Liu, Tingli" sort="Liu, Tingli" uniqKey="Liu T" first="Tingli" last="Liu">Tingli Liu</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea>
<wicri:noRegion>Nanjing 210095</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Chen, Yanyu" sort="Chen, Yanyu" uniqKey="Chen Y" first="Yanyu" last="Chen">Yanyu Chen</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea>
<wicri:noRegion>Nanjing 210095</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zhou, Jian Min" sort="Zhou, Jian Min" uniqKey="Zhou J" first="Jian-Min" last="Zhou">Jian-Min Zhou</name>
<affiliation wicri:level="1"><nlm:affiliation>Center for Genome Biology and State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Center for Genome Biology and State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101</wicri:regionArea>
<placeName><settlement type="city">Pékin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dou, Daolong" sort="Dou, Daolong" uniqKey="Dou D" first="Daolong" last="Dou">Daolong Dou</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</nlm:affiliation>
<country xml:lang="fr">République populaire de Chine</country>
<wicri:regionArea>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095</wicri:regionArea>
<wicri:noRegion>Nanjing 210095</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">Scientific reports</title>
<idno type="eISSN">2045-2322</idno>
<imprint><date when="2016" type="published">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Apoptosis Regulatory Proteins (chemistry)</term>
<term>Apoptosis Regulatory Proteins (genetics)</term>
<term>Apoptosis Regulatory Proteins (metabolism)</term>
<term>Arabidopsis (genetics)</term>
<term>Arabidopsis (immunology)</term>
<term>Arabidopsis (microbiology)</term>
<term>Arabidopsis Proteins (genetics)</term>
<term>Arabidopsis Proteins (immunology)</term>
<term>Cell Death (MeSH)</term>
<term>Gene Expression Regulation (MeSH)</term>
<term>Host-Pathogen Interactions (MeSH)</term>
<term>Phosphorylation (MeSH)</term>
<term>Phytophthora (genetics)</term>
<term>Phytophthora (growth & development)</term>
<term>Phytophthora (metabolism)</term>
<term>Plant Cells (immunology)</term>
<term>Plant Cells (microbiology)</term>
<term>Plant Diseases (genetics)</term>
<term>Plant Diseases (immunology)</term>
<term>Plant Diseases (microbiology)</term>
<term>Plant Immunity (genetics)</term>
<term>Plant Leaves (genetics)</term>
<term>Plant Leaves (immunology)</term>
<term>Plant Leaves (microbiology)</term>
<term>Plants, Genetically Modified (MeSH)</term>
<term>Protein Kinases (genetics)</term>
<term>Protein Kinases (immunology)</term>
<term>Protein Multimerization (MeSH)</term>
<term>Protein-Serine-Threonine Kinases (genetics)</term>
<term>Protein-Serine-Threonine Kinases (immunology)</term>
<term>Protoplasts (immunology)</term>
<term>Protoplasts (microbiology)</term>
<term>Pseudomonas syringae (genetics)</term>
<term>Pseudomonas syringae (metabolism)</term>
<term>Signal Transduction (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Arabidopsis (génétique)</term>
<term>Arabidopsis (immunologie)</term>
<term>Arabidopsis (microbiologie)</term>
<term>Cellules végétales (immunologie)</term>
<term>Cellules végétales (microbiologie)</term>
<term>Feuilles de plante (génétique)</term>
<term>Feuilles de plante (immunologie)</term>
<term>Feuilles de plante (microbiologie)</term>
<term>Immunité des plantes (génétique)</term>
<term>Interactions hôte-pathogène (MeSH)</term>
<term>Maladies des plantes (génétique)</term>
<term>Maladies des plantes (immunologie)</term>
<term>Maladies des plantes (microbiologie)</term>
<term>Mort cellulaire (MeSH)</term>
<term>Multimérisation de protéines (MeSH)</term>
<term>Phosphorylation (MeSH)</term>
<term>Phytophthora (croissance et développement)</term>
<term>Phytophthora (génétique)</term>
<term>Phytophthora (métabolisme)</term>
<term>Protein kinases (génétique)</term>
<term>Protein kinases (immunologie)</term>
<term>Protein-Serine-Threonine Kinases (génétique)</term>
<term>Protein-Serine-Threonine Kinases (immunologie)</term>
<term>Protoplastes (immunologie)</term>
<term>Protoplastes (microbiologie)</term>
<term>Protéines d'Arabidopsis (génétique)</term>
<term>Protéines d'Arabidopsis (immunologie)</term>
<term>Protéines régulatrices de l'apoptose (composition chimique)</term>
<term>Protéines régulatrices de l'apoptose (génétique)</term>
<term>Protéines régulatrices de l'apoptose (métabolisme)</term>
<term>Pseudomonas syringae (génétique)</term>
<term>Pseudomonas syringae (métabolisme)</term>
<term>Régulation de l'expression des gènes (MeSH)</term>
<term>Transduction du signal (MeSH)</term>
<term>Végétaux génétiquement modifiés (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Apoptosis Regulatory Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Apoptosis Regulatory Proteins</term>
<term>Arabidopsis Proteins</term>
<term>Protein Kinases</term>
<term>Protein-Serine-Threonine Kinases</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="immunology" xml:lang="en"><term>Arabidopsis Proteins</term>
<term>Protein Kinases</term>
<term>Protein-Serine-Threonine Kinases</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Apoptosis Regulatory Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Protéines régulatrices de l'apoptose</term>
</keywords>
<keywords scheme="MESH" qualifier="croissance et développement" xml:lang="fr"><term>Phytophthora</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Arabidopsis</term>
<term>Phytophthora</term>
<term>Plant Diseases</term>
<term>Plant Immunity</term>
<term>Plant Leaves</term>
<term>Pseudomonas syringae</term>
</keywords>
<keywords scheme="MESH" qualifier="growth & development" xml:lang="en"><term>Phytophthora</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Arabidopsis</term>
<term>Feuilles de plante</term>
<term>Immunité des plantes</term>
<term>Maladies des plantes</term>
<term>Phytophthora</term>
<term>Protein kinases</term>
<term>Protein-Serine-Threonine Kinases</term>
<term>Protéines d'Arabidopsis</term>
<term>Protéines régulatrices de l'apoptose</term>
<term>Pseudomonas syringae</term>
</keywords>
<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Arabidopsis</term>
<term>Cellules végétales</term>
<term>Feuilles de plante</term>
<term>Maladies des plantes</term>
<term>Protein kinases</term>
<term>Protein-Serine-Threonine Kinases</term>
<term>Protoplastes</term>
<term>Protéines d'Arabidopsis</term>
</keywords>
<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Arabidopsis</term>
<term>Plant Cells</term>
<term>Plant Diseases</term>
<term>Plant Leaves</term>
<term>Protoplasts</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Phytophthora</term>
<term>Pseudomonas syringae</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiologie" xml:lang="fr"><term>Arabidopsis</term>
<term>Cellules végétales</term>
<term>Feuilles de plante</term>
<term>Maladies des plantes</term>
<term>Protoplastes</term>
</keywords>
<keywords scheme="MESH" qualifier="microbiology" xml:lang="en"><term>Arabidopsis</term>
<term>Plant Cells</term>
<term>Plant Diseases</term>
<term>Plant Leaves</term>
<term>Protoplasts</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Phytophthora</term>
<term>Protéines régulatrices de l'apoptose</term>
<term>Pseudomonas syringae</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Cell Death</term>
<term>Gene Expression Regulation</term>
<term>Host-Pathogen Interactions</term>
<term>Phosphorylation</term>
<term>Plants, Genetically Modified</term>
<term>Protein Multimerization</term>
<term>Signal Transduction</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Interactions hôte-pathogène</term>
<term>Mort cellulaire</term>
<term>Multimérisation de protéines</term>
<term>Phosphorylation</term>
<term>Régulation de l'expression des gènes</term>
<term>Transduction du signal</term>
<term>Végétaux génétiquement modifiés</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Oomycete pathogens produce a large number of effectors to promote infection. Their mode of action are largely unknown. Here we show that a Phytophthora sojae effector, PsCRN63, suppresses flg22-induced expression of FRK1 gene, a molecular marker in pathogen-associated molecular patterns (PAMP)-triggered immunity (PTI). However, PsCRN63 does not suppress upstream signaling events including flg22-induced MAPK activation and BIK1 phosphorylation, indicating that it acts downstream of MAPK cascades. The PsCRN63-transgenic Arabidopsis plants showed increased susceptibility to bacterial pathogen Pseudomonas syringae pathovar tomato (Pst) DC3000 and oomycete pathogen Phytophthora capsici. The callose deposition were suppressed in PsCRN63-transgenic plants compared with the wild-type control plants. Genes involved in PTI were also down-regulated in PsCRN63-transgenic plants. Interestingly, we found that PsCRN63 forms an dimer that is mediated by inter-molecular interactions between N-terminal and C-terminal domains in an inverted association manner. Furthermore, the N-terminal and C-terminal domains required for the dimerization are widely conserved among CRN effectors, suggesting that homo-/hetero-dimerization of Phytophthora CRN effectors is required to exert biological functions. Indeed, the dimerization was required for PTI suppression and cell death-induction activities of PsCRN63.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">27243217</PMID>
<DateCompleted><Year>2018</Year>
<Month>04</Month>
<Day>05</Day>
</DateCompleted>
<DateRevised><Year>2018</Year>
<Month>11</Month>
<Day>13</Day>
</DateRevised>
<Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">2045-2322</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>6</Volume>
<PubDate><Year>2016</Year>
<Month>05</Month>
<Day>31</Day>
</PubDate>
</JournalIssue>
<Title>Scientific reports</Title>
<ISOAbbreviation>Sci Rep</ISOAbbreviation>
</Journal>
<ArticleTitle>A Phytophthora sojae effector PsCRN63 forms homo-/hetero-dimers to suppress plant immunity via an inverted association manner.</ArticleTitle>
<Pagination><MedlinePgn>26951</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1038/srep26951</ELocationID>
<Abstract><AbstractText>Oomycete pathogens produce a large number of effectors to promote infection. Their mode of action are largely unknown. Here we show that a Phytophthora sojae effector, PsCRN63, suppresses flg22-induced expression of FRK1 gene, a molecular marker in pathogen-associated molecular patterns (PAMP)-triggered immunity (PTI). However, PsCRN63 does not suppress upstream signaling events including flg22-induced MAPK activation and BIK1 phosphorylation, indicating that it acts downstream of MAPK cascades. The PsCRN63-transgenic Arabidopsis plants showed increased susceptibility to bacterial pathogen Pseudomonas syringae pathovar tomato (Pst) DC3000 and oomycete pathogen Phytophthora capsici. The callose deposition were suppressed in PsCRN63-transgenic plants compared with the wild-type control plants. Genes involved in PTI were also down-regulated in PsCRN63-transgenic plants. Interestingly, we found that PsCRN63 forms an dimer that is mediated by inter-molecular interactions between N-terminal and C-terminal domains in an inverted association manner. Furthermore, the N-terminal and C-terminal domains required for the dimerization are widely conserved among CRN effectors, suggesting that homo-/hetero-dimerization of Phytophthora CRN effectors is required to exert biological functions. Indeed, the dimerization was required for PTI suppression and cell death-induction activities of PsCRN63.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Li</LastName>
<ForeName>Qi</ForeName>
<Initials>Q</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation>
</AffiliationInfo>
<AffiliationInfo><Affiliation>Center for Genome Biology and State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhang</LastName>
<ForeName>Meixiang</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Shen</LastName>
<ForeName>Danyu</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Liu</LastName>
<ForeName>Tingli</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chen</LastName>
<ForeName>Yanyu</ForeName>
<Initials>Y</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Zhou</LastName>
<ForeName>Jian-Min</ForeName>
<Initials>JM</Initials>
<AffiliationInfo><Affiliation>Center for Genome Biology and State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Dou</LastName>
<ForeName>Daolong</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China.</Affiliation>
</AffiliationInfo>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2016</Year>
<Month>05</Month>
<Day>31</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>Sci Rep</MedlineTA>
<NlmUniqueID>101563288</NlmUniqueID>
<ISSNLinking>2045-2322</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D051017">Apoptosis Regulatory Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D029681">Arabidopsis Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 2.7.-</RegistryNumber>
<NameOfSubstance UI="C587207">FRK1 protein, Arabidopsis</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 2.7.-</RegistryNumber>
<NameOfSubstance UI="D011494">Protein Kinases</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 2.7.11.1</RegistryNumber>
<NameOfSubstance UI="C509522">BIK1 protein, Arabidopsis</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 2.7.11.1</RegistryNumber>
<NameOfSubstance UI="D017346">Protein-Serine-Threonine Kinases</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D051017" MajorTopicYN="N">Apoptosis Regulatory Proteins</DescriptorName>
<QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017360" MajorTopicYN="N">Arabidopsis</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D029681" MajorTopicYN="N">Arabidopsis Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016923" MajorTopicYN="N">Cell Death</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005786" MajorTopicYN="N">Gene Expression Regulation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D054884" MajorTopicYN="Y">Host-Pathogen Interactions</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010766" MajorTopicYN="N">Phosphorylation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010838" MajorTopicYN="N">Phytophthora</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000254" MajorTopicYN="N">growth & development</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D059828" MajorTopicYN="N">Plant Cells</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010935" MajorTopicYN="N">Plant Diseases</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D057865" MajorTopicYN="N">Plant Immunity</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D018515" MajorTopicYN="N">Plant Leaves</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="Y">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D030821" MajorTopicYN="N">Plants, Genetically Modified</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011494" MajorTopicYN="N">Protein Kinases</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055503" MajorTopicYN="N">Protein Multimerization</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017346" MajorTopicYN="N">Protein-Serine-Threonine Kinases</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011523" MajorTopicYN="N">Protoplasts</DescriptorName>
<QualifierName UI="Q000276" MajorTopicYN="N">immunology</QualifierName>
<QualifierName UI="Q000382" MajorTopicYN="N">microbiology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D044224" MajorTopicYN="N">Pseudomonas syringae</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015398" MajorTopicYN="N">Signal Transduction</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2016</Year>
<Month>03</Month>
<Day>16</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2016</Year>
<Month>05</Month>
<Day>05</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2016</Year>
<Month>6</Month>
<Day>1</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2016</Year>
<Month>6</Month>
<Day>1</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2018</Year>
<Month>4</Month>
<Day>6</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>epublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">27243217</ArticleId>
<ArticleId IdType="pii">srep26951</ArticleId>
<ArticleId IdType="doi">10.1038/srep26951</ArticleId>
<ArticleId IdType="pmc">PMC4886637</ArticleId>
</ArticleIdList>
<ReferenceList><Reference><Citation>PLoS Pathog. 2015 Dec 29;11(12):e1005348</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26714171</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2012;8(8):e1002875</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22927814</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Bacteriol. 1996 Nov;178(21):6399-402</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8892851</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2008 Jul;20(7):1930-47</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18621946</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Planta. 2008 Nov;228(6):977-87</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18682978</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2009 Sep 17;461(7262):393-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19741609</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell Environ. 2013 Jun;36(6):1192-203</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23237451</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Sci Rep. 2015 Jun 03;5:10837</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26039925</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2013;8(3):e59517</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23536880</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2002 Feb 28;415(6875):977-83</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11875555</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Host Microbe. 2008 Jul 17;4(1):17-27</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18621007</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Science. 2007 Oct 26;318(5850):648-51</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17962565</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2010 Feb 1;61(3):519-28</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19891705</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2014 Apr 24;10(4):e1004057</Citation>
<ArticleIdList><ArticleId IdType="pubmed">24763622</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2007 Jul 26;448(7152):497-500</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17625569</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>EMBO J. 2002 Dec 16;21(24):6681-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12485989</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2006 Feb;18(2):465-76</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16377758</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2007 Nov 1;450(7166):115-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17914356</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2011 Jan;23(1):4-15</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21278123</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2006 Dec;18(12):3721-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17194768</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2006 Nov 16;444(7117):323-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17108957</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Genome Res. 2003 Jul;13(7):1675-85</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12840044</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Host Microbe. 2010 Apr 22;7(4):290-301</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20413097</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2000 Oct;24(2):265-73</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11069700</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2010 Jun;22(6):2033-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20571112</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2007 May 17;447(7142):284-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17450127</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Plant Sci. 2012 Jul 16;3:160</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22811685</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 2015 Jan;167(1):164-75</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25424308</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Plant Pathol. 2015 May;16(4):413-34</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25178392</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS Pathog. 2011 Nov;7(11):e1002348</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22072967</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2006 Jul;18(7):1766-77</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16766692</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2015 Jul;27(7):2057-72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26163574</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2010 May 25;107(21):9909-14</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20457921</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17421-6</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20847293</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 2011 Jan;155(1):490-501</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21071601</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Biol. 2008 Jan 8;18(1):74-80</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18158241</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Opin Microbiol. 2011 Feb;14(1):54-61</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21215683</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Mol Cell. 2000 Jun;5(6):1003-11</Citation>
<ArticleIdList><ArticleId IdType="pubmed">10911994</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Nature. 2012 Apr 15;485(7396):114-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22504181</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2011 Sep;23(9):3498-511</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21917550</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 2004 Jan 9;279(2):1132-40</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14578352</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2006 Oct;48(2):165-76</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16965554</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8577-82</Citation>
<ArticleIdList><ArticleId IdType="pubmed">12817082</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2008 Mar 25;105(12):4874-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18344324</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2015 May 26;10(5):e0127965</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26011314</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16955-60</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25368167</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Physiol. 2009 Aug;150(4):1648-55</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19420325</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2011 Jun;23(6):2064-86</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21653195</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Host Microbe. 2012 Oct 18;12(4):484-95</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23084917</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Host Microbe. 2007 May 17;1(3):175-85</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18005697</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant Cell. 2012 Mar;24(3):1256-70</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22427336</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12539-44</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21737749</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Plant J. 2012 Feb;69(3):489-500</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21974727</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Host Microbe. 2012 Mar 15;11(3):253-63</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22423965</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Host Microbe. 2013 Feb 13;13(2):143-54</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23414755</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Biol. 2008 Dec 9;18(23):1824-32</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19062288</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2013 Jul 29;8(7):e70036</Citation>
<ArticleIdList><ArticleId IdType="pubmed">23922898</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12990-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">16123135</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Annu Rev Phytopathol. 2008;46:189-215</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18422429</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>République populaire de Chine</li>
</country>
<settlement><li>Pékin</li>
</settlement>
</list>
<tree><country name="République populaire de Chine"><noRegion><name sortKey="Li, Qi" sort="Li, Qi" uniqKey="Li Q" first="Qi" last="Li">Qi Li</name>
</noRegion>
<name sortKey="Chen, Yanyu" sort="Chen, Yanyu" uniqKey="Chen Y" first="Yanyu" last="Chen">Yanyu Chen</name>
<name sortKey="Dou, Daolong" sort="Dou, Daolong" uniqKey="Dou D" first="Daolong" last="Dou">Daolong Dou</name>
<name sortKey="Li, Qi" sort="Li, Qi" uniqKey="Li Q" first="Qi" last="Li">Qi Li</name>
<name sortKey="Liu, Tingli" sort="Liu, Tingli" uniqKey="Liu T" first="Tingli" last="Liu">Tingli Liu</name>
<name sortKey="Shen, Danyu" sort="Shen, Danyu" uniqKey="Shen D" first="Danyu" last="Shen">Danyu Shen</name>
<name sortKey="Zhang, Meixiang" sort="Zhang, Meixiang" uniqKey="Zhang M" first="Meixiang" last="Zhang">Meixiang Zhang</name>
<name sortKey="Zhou, Jian Min" sort="Zhou, Jian Min" uniqKey="Zhou J" first="Jian-Min" last="Zhou">Jian-Min Zhou</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Bois/explor/PhytophthoraV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000D27 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000D27 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Bois
   |area=    PhytophthoraV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:27243217
   |texte=   A Phytophthora sojae effector PsCRN63 forms homo-/hetero-dimers to suppress plant immunity via an inverted association manner.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:27243217" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a PhytophthoraV1

This area was generated with Dilib version V0.6.38.
Data generation: Fri Nov 20 11:20:57 2020. Site generation: Wed Mar 6 16:48:20 2024

	Serveur d'exploration Phytophthora
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration Phytophthora

A Phytophthora sojae effector PsCRN63 forms homo-/hetero-dimers to suppress plant immunity via an inverted association manner.

A Phytophthora sojae effector PsCRN63 forms homo-/hetero-dimers to suppress plant immunity via an inverted association manner.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki